Copper-catalyzed asymmetric conjugate addition of diethylzinc to substituted chalcones using a chiral phosphine ligand

DOĞAN Ö., BULUT A., Polat S., Ali Tecimer M.

Tetrahedron Asymmetry, cilt.22, sa.16-17, ss.1601-1604, 2011 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 16-17
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1016/j.tetasy.2011.09.003
  • Dergi Adı: Tetrahedron Asymmetry
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1601-1604
  • Lokman Hekim Üniversitesi Adresli: Hayır

Özet

A series of chiral phosphine PFAM and phosphine oxide POFAM ligands were studied for the copper-catalyzed asymmetric diethylzinc addition to enones. One of these ligands, PFAM2, was an efficient catalyst with a variety of enones to give conjugate addition products in up to 96% yield and 92% ee. Copyright © 2011 Published by Elsevier Ltd. All rights reserved.