Akademik Veri Yönetim Sistemi
TARIM BILIMLERI DERGISI, cilt.31, sa.3, ss.835-845, 2025 (SCI-Expanded)
Polygonum species have strong biological activity due to their important
bioactive components. Polygonum species have been studied for enzyme
inhibition activity, wound healing, anti-inflammatory, antibacterial,
antiviral, antioxidant effects, immunomodulatory activity, anti-aging
potential, estrogenic activity and are used abroad as a source of
resveratrol. For this purpose, biological activity studies, and
phytochemical analysis were carried out in P. aviculare L., P. cognatum
Meissn., P. patulum Bieb. subsp. patulum, and P. setosum Jacq. subsp.
setosum growing in Turkish flora. Polygonum ethanol extracts were tested
for their cholinesterase, elastase, collagenase, and tyrosinase enzyme inhibitory activities with spectrophotometry. P. aviculare root extract had
the highest acetylcholinesterase inhibitory activity (IC50= 55.94 ± 2.63
µg/mL), while the best butrylcholinesterase inhibitory activity was
observed for P. aviculare (IC50= 17.02 ± 3.42 µg/mL) and P. patulum
(IC50= 18.36 ± 0.15). µg/mL) root extracts. All Polygonum root extracts
showed moderate inhibitory activity against tyrosinase. In this study
indicated that P. aviculare root (IC50= 169.33 ± 3.58 µg/mL) had the
highest anti-elastase activity. P. cognatum roots (IC50= 200.30 ± 2.26
µg/mL) have potent inhibition against collagenase. LC-Q-ToF-MS
analysis in Polygonum extracts indicated that resveratrol was not present
in the extracts.