Induction of cytokines by a phenylpropanoid glycoside acteoside
BIOLOGICAL & PHARMACEUTICAL BULLETIN, cilt.21, sa.12, ss.1394-1395, 1998 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 21 Sayı: 12
- Basım Tarihi: 1998
- Doi Numarası: 10.1248/bpb.21.1394
- Dergi Adı: BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1394-1395
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Lokman Hekim Üniversitesi Adresli: Hayır
Özet
A phenylpropanoid glycoside acteoside was found to induce interleukin (IL)-1, IL-6, and tumor necrosis factor-a (TNF-alpha) in macrophage-like cell line J774.A1 at 1-100 ng/ml, In addition,, when the stimulatory action of acteoside was studied using the bovine glomerular endothelial cell line GEN-T, it stimualted IL-6 production. These stimulatory activities were not abolished by treatment with polymixin B, which inactivates lipopolysaccharide (LPS), indicating that the action was not a contamination of LPS.