CTX-M-3 extended-spectrum β-lactamase in a Shigella sonnei clinical isolate: First report from Turkey

Acikgoz Z. C., Gulay Z., Bicmen M., Gocer S., Gamberzade S.

Scandinavian Journal of Infectious Diseases, vol.35, no.8, pp.503-505, 2003 (SCI-Expanded) identifier identifier identifier


A Shigella sonnei strain resistant to cefotaxime and aztreonam (but not ceftazidime) was isolated from the stool sample of a 7-y-old outpatient. Double disk synergy test, isoelectric focusing, polymerase chain reaction and sequence analysis confirmed that the isolate produced CTX-M-3, an extended-spectrum β-lactamase (ESBL). This is the first report from Turkey of Shigella spp. producing an ESBL, and of CTX-M type enzyme.