The effect of pentoxiphylline, a nonspecific phospodiesterase inhibitor, on angiogenesis in chicken chorioallantoic membrane (CAM) model

ALTUNTAŞ E. E., Balaban H., Uysal I., Akin P.

HealthMED, vol.5, no.6 SUPPL. 1, pp.1841-1846, 2011 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 5 Issue: 6 SUPPL. 1
  • Publication Date: 2011
  • Journal Name: HealthMED
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1841-1846
  • Keywords: Angiogenesis, Chicken chorio-allantoic membrane, In vivo, Pentoxifylline, Phosphodiesterase inhibitor
  • Lokman Hekim University Affiliated: No

Abstract

Objectives: Based on a neovascularization study conducted using specific phosphodiesterase inhibitors in the literature, the aim of the present study was to answer the question "As specific phosphodiesterase inhibitors have positive or negative effects on angiogenesis, what kind of an effect does pentoxiphylline, which is a phosphodie-sterase inhibitor, have on angiogenesis?" by using chorioallantoic membrane model.