Does Atopy Affect the Radiological Extent of Pulmonary Tuberculosis?

Kutlu A., Bozkurt B., Ciftci F., Bozkanat E., Gorur R., Sonmez G., ...Daha Fazla

ALLERGOLOGIA ET IMMUNOPATHOLOGIA, cilt.36, sa.4, ss.187-190, 2008 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36 Sayı: 4
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/s0301-0546(08)72547-3
  • Dergi Adı: ALLERGOLOGIA ET IMMUNOPATHOLOGIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.187-190
  • Anahtar Kelimeler: Mycobacterium tuberculosis, Atopy, Skin prick test, Radiological dissemination, MYCOBACTERIUM-TUBERCULOSIS, IL-4, INFECTION, RESPONSES, MICE
  • Lokman Hekim Üniversitesi Adresli: Hayır

Özet

Background: Th1 cytokines, IL-2 and IFN-gamma, have critical importance in the CD4 cell driven antimy-cobacterial activity. Th2 type immune response is a characteristic feature of atopic disorders. Th1 and Th2 cells have been reported to negatively cross-regulate each other in vitro and in experimental animals. Our aim in the present study is to determine whether the atopy affects radiological extent of pulmonary tuberculosis (TB) and disease severity.