Bilateral Xen® is Used as Minimally Invasive Glaucoma Surgery for Glaucoma in GAPO Syndrome: Case Report

Eraslan M., Turkoglu C., Biberoglu E.

Journal of the College of Physicians and Surgeons Pakistan, vol.35, no.1, pp.51-53, 2025 (SCI-Expanded, Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 1
  • Publication Date: 2025
  • Doi Number: 10.29271/jcpspcr.2025.51
  • Journal Name: Journal of the College of Physicians and Surgeons Pakistan
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.51-53
  • Keywords: GAPO syndrome, Micro-stent, Minimally invasive glaucoma surgeries, Primary open-angle glaucoma
  • Lokman Hekim University Affiliated: Yes

Abstract

The GAPO syndrome is a rare congenital disease that includes growth retardation (G), alopecia (A), pseudo-anodontia (P), and progressive optic atrophy (O). Glaucoma is a well-known disorder reported in GAPO cases. A 36-year woman, a previously diagnosed case of GAPO syndrome, has been followed up in our glaucoma clinic with primary open-angle glaucoma since 2012. In this report, we present her case which underwent XEN® gelatin micro-stent implantation in both eyes at two-week intervals because of uncontrolled primary open-angle glaucoma on medical therapy. To the best of our knowledge, this is the first patient with GAPO syndrome who underwent XEN® gelatin implantation via minimal invasive glaucoma surgery (MIGS). The MIGSs are proper options in GAPO syndrome with primary open-angle glaucoma resistant to medical treatment.