Akademik Veri Yönetim Sistemi
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, cilt.12, sa.1, ss.989-996, 2019 (SCI-Expanded)
The aim of this study was to determine the incidence and risk factors of infections associated with implantable venous access ports (IVAPs) in adult patients with hematological cancer. A retrospective analysis was made of patients with hematological malignancies in the adult Hematology Department between December 2014 and December 2016. IVAP was inserted in a total of 87 patients in the Interventional Radiology Department. Evaluation was made of the incidence of port-related infections, patient characteristics, bacteriological data and patient progress. Univariable analyses (Chi-square test and Mann-Whitney U test) and multiple logistic regression analyses were used to determine the risk factors for IVAP-related infection. The study included 87 patients applied with IVAP. There was a total of 21823 catheter/day follow-up. IVAP-related infection was observed in 13 cases (14.9%). Total incidence of IVAP-related bloodstream infections (BSIs) was 0.595 events/1000 catheter days. Coagulase-negative staphylococci were the pathogens most commonly isolated. In logistic regression analysis, factors that increased the risk for IVAP-related infections were neutropenia on the day of implantation (OR = 4.139; P < 0.05) and the number of chemotherapy lines received after IVAP insertion (OR = 2.126; P < 0.05). The median time without IVA-Prelated BSI was 62 days (range, 10-382 days). Neutropenia on the day of implantation and the number of chemotherapy lines after IVAP insertion were independent risk factors for IVAP-related BSIs. Therefore, it can be suggested that, as far as possible, ports should be inserted after the neutropenia period in these patients.