Microchemical Journal, cilt.159, 2020 (SCI-Expanded)
© 2020 Elsevier B.V.Recent advances in wearable sensor technologies have enormous potential for early diagnosis and personalized medicine. Although wearable sweat sensors have been designed in various approaches, including electronics and electrochemical methods, reliable and low-cost methods for monitoring sweat volume and pH remains a challenge. Here, sodium polyacrylate (SP) microparticle containing multifunctional skin patch was developed for local sweat volume and pH analysis. The wearable skin patch monitors local sweat volume and rate by wicking of sweat into SP hydrogel microparticles. In this approach, the circular geometry of the hydrogel microparticles measures sweat volume and, therefore, sweat rate. Also, this patch contains pH monitoring system which provides colorimetric response for sweat analysis. Moreover, an easy-to-use, smartphone integrated wearable sensor system for local sweat volume analysis is introduced. Multifunctional wearable skin patch showed rapid, reliable and predictable results under various sweat physiological conditions such as pH (pH 4, pH 6, pH 7 and pH 9), NaCI (30, 60 and 90 mM), KCI (5, 10 and 20 mM) and urea (10, 20 and 30 mM). The advantages of the proposed method are seen in simple, fast, and low-cost fabrication of multifunctional wearable sensors that accurately monitor local sweat volume.