Chrysin: Pharmacological and therapeutic properties

Naz S., Imran M., Rauf A., ERDOĞAN ORHAN İ., Shariati M. A., Iahtisham-Ul-Haq I., ...More

LIFE SCIENCES, vol.235, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 235
  • Publication Date: 2019
  • Doi Number: 10.1016/j.lfs.2019.116797
  • Journal Name: LIFE SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: Chrysin, Flavonoids, Antioxidant, Cytotoxic, Anti-inflammatory, Health claims, INDUCED OXIDATIVE STRESS, IN-VITRO, ALLERGIC INFLAMMATION, FLAVONOID CHRYSIN, PROTECTIVE ROLE, PROBABLE ROLE, CO-DELIVERY, RATS, INJURY, DAMAGE
  • Lokman Hekim University Affiliated: No

Abstract

Chrysin is a promising phytochemical that is categorized under the class of flavonoids based on its chemical structure. Naturally, it is widely present in propolis, honey, passion fruit, and even in mushrooms and other plant sources, whereas its synthetic counterparts are also being employed for pharmacological purposes. It has widely been employed in treatment of various degenerative disorders and provides cytotoxic and anti-inflammatory functions. Its antioxidant and disease preventing abilities are attributed to its structural diversity arising in ring-A and absence of oxygenation in B and C ring. In this review, the scientific studies are being reported emphasizing benefits and its allied health claims on chrysin in numerous metabolic malfunctions.