Simultaneous determination of niclosamide and thiabendazole in tablets by second derivative spectrophotometry
Gazi Universitesi Eczacilik Fakultesi Dergisi, cilt.11, sa.1, ss.33-42, 1994 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 11 Sayı: 1
- Basım Tarihi: 1994
- Dergi Adı: Gazi Universitesi Eczacilik Fakultesi Dergisi
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.33-42
- Anahtar Kelimeler: niclosamide, pharmaceutical preparations, second derivative spectrophotometry, simultaneous determination, thiabendazole
- Lokman Hekim Üniversitesi Adresli: Hayır
Özet
Rapid second derivative spectrophotometric assay procedure is described for the simultaneous determination of niclosamide and thiabendazole in a pharmaceutical preparation. In this method the derivative absorbances were measured at 354,0 nm for niclosamide and at 242,5 nm for thiabendazole. The method has been applied succesfully to a tablet containing niclosamide and thiabendazole. The relative standard deviation of the method was found to be 1,19% for niclosamide and 0,51% for thiabendazole.