Three new spectrophotometric methods for simultaneous determination of hydrochlorothiazide and amiloride hydrochloride in sugar-coated tablets

ERK N., ONUR F.

Analytical Letters, cilt.30, sa.8, ss.1503-1515, 1997 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 8
  • Basım Tarihi: 1997
  • Doi Numarası: 10.1080/00032719708001671
  • Dergi Adı: Analytical Letters
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1503-1515
  • Anahtar Kelimeler: Amiloride hydrochloride, Hydrochlorothiazide, Pharmaceutical preparations, Simultaneous determination, Spectrophotometry
  • Lokman Hekim Üniversitesi Adresli: Hayır

Özet

Three new spectrophotometric methods, Vierordt's method, its modified version and the absorbancy ratio method have been used for the simultaneous determination of hydrochlorothiazide and amiloride hydrochloride in binary mixtures. Mean recoveries, relative standard deviations and linearity ranges in calibration graphs of the methods were compared. These three methods have been successfully applied to a commercial pharmaceutical preparation, a sugar-coated tablet containing hydrochlorothiazide and amiloride hydrochloride.