Influence of CPAP treatment on airway and systemic inflammation in OSAS patients

Karamanli H., Ozol D., Ugur K. S., Yildirim Z., Armutcu F., Bozkurt B., ...Daha Fazla

SLEEP AND BREATHING, cilt.18, sa.2, ss.251-256, 2014 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 2
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1007/s11325-012-0761-8
  • Dergi Adı: SLEEP AND BREATHING
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.251-256
  • Anahtar Kelimeler: Sleep apnea, CPAP, Inflammation, Oxidative stress, OBSTRUCTIVE SLEEP-APNEA, EXHALED BREATH CONDENSATE, PRACTICE PARAMETERS, NITRIC-OXIDE
  • Lokman Hekim Üniversitesi Adresli: Hayır

Özet

Obstructive sleep apnea syndrome (OSAS) is characterized by recurrent respiratory disorders in the upper airways during sleep. Although continuous positive airway pressure (CPAP) has been accepted to be the most effective treatment for OSAS, its role on inflammation remains debatable. In this study, our aim was to examine the influence of 3 months of CPAP treatment on tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), 8-isoprostane, and peroxynitrite levels in exhaled breathing condensates (EBC) and serum.