Relation between lymphocyte to monocyte ratio and short-term mortality in patients with acute pulmonary embolism

Ertem A. G., Yayla C., AÇAR B., KIRBAŞ Ö., Unal S., Uzel Sener M., ...More

Clinical Respiratory Journal, vol.12, no.2, pp.580-586, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 2
  • Publication Date: 2018
  • Doi Number: 10.1111/crj.12565
  • Journal Name: Clinical Respiratory Journal
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.580-586
  • Keywords: acute pulmonary embolism, inflammation, lymphocyte to monocyte ratio, mortality, C-REACTIVE PROTEIN, SEVERITY INDEX, MYOCARDIAL-INFARCTION, OXIDATIVE STRESS, OUTCOMES, INFLAMMATION, MANAGEMENT, ISCHEMIA, MARKER, COUNT
  • Lokman Hekim University Affiliated: No

Abstract

© 2016 John Wiley & Sons LtdIntroduction: The relationship between inflammation and mortality after acute pulmonary embolism (APE) has previously been investigated with different variables (platelet/lymphocyte ratio, etc). Objectives: We investigated the predictive value of lymphocyte to monocyte ratio (LMR) for mortality in first 30 days after APE. Methods: The study population included 264 APE patients of which 230 patients were survivors, 34 patients were non-survivors. Results: LMR was significantly lower in non-survivors after APE (P <.001). Neutrophil-to-lymphocyte ratio (NLR) was higher in non-survivors after APE (P <.001). Platelet-to-lymphocyte (PLR) had no significance between both groups (P:.241). Simplified pulmonary embolism severity index and LMR were independent predictors of mortality in patients with APE (P:.008 and P:.001, respectively). Conclusion: LMR as a novel marker of inflammation seemed to be an independent predictor of short-term mortality in patients with APE.