Urinary methylmalonic acid levels in patients with acute ischemic stroke

Kara N., Senes M., Coskun O., Inan L., Saydam G., Yucel D.

CLINICAL BIOCHEMISTRY, cilt.42, sa.7-8, ss.578-583, 2009 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 42 Sayı: 7-8
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1016/j.clinbiochem.2009.02.018
  • Dergi Adı: CLINICAL BIOCHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.578-583
  • Anahtar Kelimeler: Folic acid, Homocysteine, Ischemic stroke, Methylmalonic acid, Vitamin B-12, FOLIC-ACID, FOLATE-DEFICIENCY, VITAMIN-B-12 DEFICIENCY, CARDIOVASCULAR-DISEASE, LIQUID-CHROMATOGRAPHY, COBALAMIN DEFICIENCY, PLASMA HOMOCYSTEINE, SERUM COBALAMIN, OLDER PERSONS, RISK
  • Lokman Hekim Üniversitesi Adresli: Hayır

Özet

Objectives: Vitamin B-12 and folate deficiency are common, especially in people aged 55 or over, and accompanied by elevated methylmalonic acid (MMA) and homocysteine concentrations. The aims of the study were to investigate the relationship between serum vitamin B-12, homocysteine, folate, erythrocyte folate and urinary MMA in patients with ischemic stroke, and to develop a simple screening HPLC method for the measurement of urinary MMA.