An Evaluation Functional Capacity in Relation to Dyspnea and Fatigue, Muscle Strength, and Dynamic Balance in Patients with Liver Transplantation

Taşkın B., Vardar Yağlı N., Çalık-Kütükcü E., Sağlam M., Inal İnce D., Doğrul A. B.

EUROPEAN RESPIRATORY JOURNAL, vol.63, no.54, pp.63, 2019 (SCI-Expanded)



Purpose: Although liver transplantation (LT) is a therapeutic method in chronic liver diseases, the effects of the disease do not completely improve after transplantation. Our study was aimed to determine functional capacity as well as dyspnea, fatigue, muscle strength, and dynamic balance, in patients with LT, and determine whether these parameters were related to the six-minute walking test (6MWT).

Methods: A total seventeen patients (6 females, 11 males, mean age: 40.56±15.73 yrs, body mass index (BMI): 25.17±4.21 kg/m2, time after LT: 61.58±72.66 months) were included in this study. The 6MWT and the timed up and go test (TUG) used to evaluate functional capacity and dynamic balance. Exercise dyspnea and fatigue perception was evaluated using the Modified Borg Scale (MBS). Lower and upper extremity strength were determined using the chair stand test, the number of standing up during 30 s, and the arm curl test, respectively.

Results: The mean 6MWT distance was 475.43±156.72 m and %6MWT distance was 68.23±21.75%. The 6MWT distance was correlated TUG times (r=-0.870, p<0.001), chair stands (r=0.580, p=0.018) and arm curls (r=0.678, p=0.004). No correlations between the 6MWT distances and dyspnea (r= -0.222, p=0.409) and fatigue (r= -0.270, p=0.511). The number of chair stands was correlated with the dyspnea (r= -0.542, p=0.030) and fatigue perceptions (r= -0.514, p=0.042).

Conclusion: The functional capacity, muscle strength and dynamic balance were reduced in LT. Decreased lower extremity strength indicated increased exercise dyspnea and fatigue. The pathological process of the disease may be caused to these results.