Mycotoxins: Toxic effects, degradations, prevention of the occurrence, and decreasing of the harmful effects Mikotosinler: Toksik etkileri, degredasyonlari, oluşumlarinin önlenmesi ve zararli etkilerinin azaltilmasi

Sabuncuoǧlu S. A. , BAYDAR T., Giray B. , Şahin G.

Hacettepe University Journal of the Faculty of Pharmacy, vol.28, no.1, pp.63-92, 2008 (Refereed Journals of Other Institutions) identifier

  • Publication Type: Article / Review
  • Volume: 28 Issue: 1
  • Publication Date: 2008
  • Title of Journal : Hacettepe University Journal of the Faculty of Pharmacy
  • Page Numbers: pp.63-92
  • Keywords: Degradation, Mycotoxins, Prevention, Toxic effect


In food, molds produce metabolites called the mycotoxins that are hazardous to public health. Together with their toxic and adverse effects on public health; they also bring economic burden on the population. Mycotoxins have carcinogenic, teratogenic, and mutagenic effects; furthermore they cause several toxic effects such as hepatotoxicity, nephrotoxicity, immune system disorders, growth retardation, and dysfunction in reproductive system. Investigations are performed to diminish their harmful effects and to prevent the formation of these toxins which cause a cardinal problem in the developing countries and the whole world. There are physical techniques, natural or synthetic chemicals and biologic methods that are used to prevent harmful effects and risks that originate from mycotoxins as well as prevention of their occurrence. In the present review, current literature related to major toxic effects of primary mycotoxins, degradations, prevention of the occurrence and decreasing of their harmful effects are summarized.