Cytokine concentrations in pediatric patients with Crimean-Congo hemorrhagic fever

TEZER H., Ozkaya-Parlakay A., Kizilgün M., Kaya A., Gulhan B., Yüksek S. K., ...More

Pediatric Infectious Disease Journal, vol.33, no.11, pp.1185-1187, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 11
  • Publication Date: 2014
  • Doi Number: 10.1097/inf.0000000000000398
  • Journal Name: Pediatric Infectious Disease Journal
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1185-1187
  • Keywords: Crimean-Congo hemorrhagic fever, children, cytokine, mortality, NECROSIS-FACTOR-ALPHA, CLINICAL-FEATURES, RIBAVIRIN THERAPY, VIRUS-INFECTION, EASTERN TURKEY, CHILDREN, OUTBREAK, IL-10
  • Lokman Hekim University Affiliated: No

Abstract

Copyright © 2014 by Lippincott Williams & Wilkins.Crimean-Congo hemorrhagic fever is a zoonotic disease that can be a severe illness in humans. We investigated concentrations of interleukin (IL)-6, tumor necrosis factor-α and IL-10 in serum samples obtained from 25 pediatric Crimean-Congo hemorrhagic fever cases and 35 control children with no signs of infection. Lower cytokine values in our patients could be a good prognostic factor to for a better outcome.