GENETIC DIVERSITY OF ACINETOBACTER BAUMANNII STRAINS ISOLATED FROM DIFFERENT HOSPITALS FARKLI HASTANELERDEN İZOLE EDİLEN ACİNETOBACTER BAUMANNİİ SUŞLARININ GENETİK ÇEŞİTLİLİĞİ

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EROL H. B., KAŞKATEPE B., ALTANLAR N., YILDIZ S., Yalcin S.

Ankara Universitesi Eczacilik Fakultesi Dergisi, cilt.47, sa.1, ss.104-110, 2023 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 1
  • Basım Tarihi: 2023
  • Doi Numarası: 10.33483/jfpau.1168215
  • Dergi Adı: Ankara Universitesi Eczacilik Fakultesi Dergisi
  • Derginin Tarandığı İndeksler: Scopus, Central & Eastern European Academic Source (CEEAS), EMBASE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.104-110
  • Anahtar Kelimeler: Acinetobacter baumannii, ERIC-PCR, genetic diversity, resistance
  • Lokman Hekim Üniversitesi Adresli: Evet

Özet

Objective: The genotypic analysis of the strains can provide information to evaluate the genetic relationships among strains and epidemiological investigations, and it is crucial for monitoring their circulation in different geographic regions. This study was to aim to identify genetic similarities or dissimilarities among clinical Acinetobacter baumannii (A. baumannii) isolates from four different hospitals. Material and Method: In this study, 78 non-duplicate clinical isolates of A. baumannii were received from patients in the critical care units. The colistin MIC values of 24 A. baumannii strains randomly selected from four different hospitals and known to have antibiotic susceptibility were determined. These strains were genetically characterized by the Enterobacterial repetitive intergenic consensus (ERIC)-PCR method. Result and Discussion: The results of the study showed that the isolates were divided into 2 clusters (A1 and A2) and Cluster A2 was represented by a single genotype (C1) and 23 interrelated genotypes were in Cluster A1.