Silver nanoparticle based analysis of aminoglycosides


ÇAĞLAYAN M. G., ONUR F.

Spectroscopy Letters, vol.47, no.10, pp.771-780, 2014 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 10
  • Publication Date: 2014
  • Doi Number: 10.1080/00387010.2013.845577
  • Journal Name: Spectroscopy Letters
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.771-780
  • Keywords: amikacin, gentamicin, milk analysis, silver nanoparticle, tobramycin, PERFORMANCE LIQUID-CHROMATOGRAPHY, SOLID-PHASE EXTRACTION, PRECOLUMN DERIVATIZATION, SPECTROPHOTOMETRIC DETERMINATION, POSTCOLUMN DERIVATIZATION, GENTAMICIN SULFATE, TRACE ANALYSIS, AMIKACIN, TOBRAMYCIN, KANAMYCIN
  • Lokman Hekim University Affiliated: No

Abstract

Colorimetric silver nanoparticle sensor was developed for determination of aminoglycosides in milk. Silver nanoparticles were synthesized by using sodium borohydride as reducing agent and sodium dodecyl sulfate as stabilizer. Yellow color of silver turned into orange and red in proportion to the concentrations of analytes. Quantitative analyses were performed by using decrease in absorbance of silver nanoparticles at 394 nm. Linear ranges were 20-60 ng mL-1, 23-60 ng mL-1, and 60-100 ng mL-1 for gentamicin, tobramycin, and amikacin, respectively. The method was optimized in terms of pH, ionic strength, and time. This simple and validated method was applied to milk samples and pharmaceutical preparations. © 2014 Taylor & Francis Group, LLC.