Clinical Practice Update on the Evaluation, Diagnosis, and Management of Pancreatic Exocrine Insufficiency: Expert Review

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Sezgin O., Oğuz D., SOYTÜRK M., Kalkan İ. H., BENGİ G., GÜL Ö.

Turkish Journal of Gastroenterology, vol.37, no.5, pp.534-554, 2026 (SCI-Expanded, Scopus, TRDizin) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 37 Issue: 5
  • Publication Date: 2026
  • Doi Number: 10.5152/tjg.2026.25679
  • Journal Name: Turkish Journal of Gastroenterology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.534-554
  • Keywords: Exocrine pancreatic insufficiency, pancreatic enzyme replacement therapy, review
  • Open Archive Collection: AVESIS Open Access Collection
  • Lokman Hekim University Affiliated: Yes

Abstract

Pancreatic exocrine insufficiency (PEI) is characterized by inadequate synthesis, secretion, and/or activation of exocrine pancreatic secretions. This guideline has been developed to assist clinicians and researchers in understanding the definition, etiopathogenesis, epidemiology, diagnosis, treatment, and follow-up of PEI based on the current literature. All statements within this review were developed through consensus among the authors based on a comprehensive literature review.