Are preservatives necessary in 24-hour urine measurements?

Yilmaz G., Yilmaz F. M., Hakligor A., Yucel D.

CLINICAL BIOCHEMISTRY, vol.41, no.10-11, pp.899-901, 2008 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 10-11
  • Publication Date: 2008
  • Doi Number: 10.1016/j.clinbiochem.2008.03.002
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.899-901
  • Keywords: urine collection, calcium, magnesium, phosphate, uric acid, preservative, UROLITHIASIS, COLLECTION, CALCIUM, SAMPLES
  • Lokman Hekim University Affiliated: No


Background: 24-h urine measurements are used in the routine diagnosis and follow-up of many diseases in the clinical laboratory. Calcium (Ca(2+)), magnesium (Mg(2+) phosphate PO(4)(3-)) and uric acid are frequently requested markers in 24-h urine samples. Because of the different solubilities of these parameters, different urine collection conditions - urine in base for uric acid and urine in acid for Ca(2+), PO(4)(3-) and Mg(2+) measurements - are recommended.