Akademik Veri Yönetim Sistemi
Ankara Universitesi Eczacilik Fakultesi Dergisi, cilt.40, sa.3, ss.41-46, 2016 (Scopus)
© 2016 Tasar?m.For veterinary injectable preparations such as human preparations, primarily it is necessary to determine the risks of microbiological contamination for microbiological quality which may occur during production and take necessary precautions related to this. In this study it was aimed to examine sterility and microbiological quality control of veterinary injectable vitamin preparations, which were manufactured in Turkey and procured from various drug depots, using membrane filtration technique. A total of 50 veterinary injectable vitamin preparations, 23 of which were fat-soluble and 27 of which were water-soluble, were studied. Contamination was observed in 5 of the total injectable preparations. Microorganisms isolated from these samples were identified as Bacillus polymyxa, Bacillus brevis and Staphylococcus aureus. It was believed that these bacteria, which caused contamination in the drugs, might be originated from the air, the manufacturing area, the equipment and the staff during the manufacturing processes.