Methicillin-resistant Staphylococcus aureus (MRSA) osteomyelitis of the mandible


Tuzuner-Oncul A. M., Ungor C., Dede U., KİŞNİŞCİ R. Ş.

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology, cilt.107, sa.6, 2009 (SCI-Expanded) identifier identifier identifier

Özet

Methicillin-resistant Staphylococcus aureus (MRSA) is a type of Staphylococcus that is resistant to certain antibiotics, such as methicillin, oxacillin, penicillin, and amoxicillin. This nosocomial pathogen has become a great threat in hospitals globally. Up to 40% of the normal population carries S. aureus in the anterior nares, and this rate is often higher in hospitalized patients and their attendants. This case report presents a patient with serious MRSA osteomyelitis of the mandible demonstrating purulent discharge. The patient failed to recover despite prolonged postoperative treatment and the administration of several antibiotics. There was a resulting nonunion along with chronic MRSA infection. The treatment protocol involved a multimodal approach with parenteral clindamycin infusion, local rifampicin irrigation, and intermaxillary fixation of the jaws. © 2009 Mosby, Inc. All rights reserved.