Thinning of Choroidal Thickness in Patients with Rheumatoid Arthritis Unrelated to Disease Activity

Duru N., Altinkaynak H., Erten Ş., Can M. E., Duru Z., Uğurlu F. G., ...More

Ocular Immunology and Inflammation, vol.24, no.3, pp.246-253, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 3
  • Publication Date: 2016
  • Doi Number: 10.3109/09273948.2015.1024329
  • Journal Name: Ocular Immunology and Inflammation
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.246-253
  • Keywords: Choroid, enhanced depth imaging optical coherence tomography, optical coherence tomography, perifoveal choroidal thickness, rheumatoid arthritis, subfoveal choroidal thickness, OPTICAL COHERENCE TOMOGRAPHY, RETINAL VASCULITIS, MACULAR DEGENERATION, OCULAR PERFUSION, BLOOD-FLOW, AGE, EYES, ASSOCIATION, IMPROVEMENT, EXPRESSION
  • Lokman Hekim University Affiliated: No


© 2016 Taylor & Francis Group, LLC.Abstract: Purpose: To investigate subfoveal and perifoveal choroidal thickness (CT) in patients with rheumatoid arthritis (RA). Methods: A study group of 117 patients with RA and a control group of 46 age-matched healthy individuals were enrolled in the study. Subfoveal and perifoveal CTs were measured using enhanced depth imaging optical coherence tomography (EDI-OCT). Perifoveal CT was measured 1,500 µm nasally and 1,500 µm temporally apart from the foveal center. Relationship between the disease activity score 28 (DAS-28) and subfoveal CT was also evaluated. Results: The mean subfoveal CT values in the study and control groups were 226.90 ± 43.61 μm and 299.74 ± 48.06 μm, respectively, which made for a statistically significant difference (p < 0.001). Likewise, perifoveal CT values were significantly thinner in the study group when compared with control group. DAS-28 wasn’t correlated with subfoveal CT in the study group. Conclusions: CT was significantly thinner in patients with RA when compared with healthy controls.