Thinning of Choroidal Thickness in Patients with Rheumatoid Arthritis Unrelated to Disease Activity

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Duru N., Altinkaynak H., Erten Ş., Can M. E., Duru Z., Uğurlu F. G., ...More

Ocular Immunology and Inflammation, vol.24, no.3, pp.246-253, 2016 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 24 Issue: 3
• Publication Date: 2016
• Doi Number: 10.3109/09273948.2015.1024329
• Journal Name: Ocular Immunology and Inflammation
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.246-253
• Keywords: Choroid, enhanced depth imaging optical coherence tomography, optical coherence tomography, perifoveal choroidal thickness, rheumatoid arthritis, subfoveal choroidal thickness, OPTICAL COHERENCE TOMOGRAPHY, RETINAL VASCULITIS, MACULAR DEGENERATION, OCULAR PERFUSION, BLOOD-FLOW, AGE, EYES, ASSOCIATION, IMPROVEMENT, EXPRESSION
• Lokman Hekim University Affiliated: No

Abstract

© 2016 Taylor & Francis Group, LLC.Abstract: Purpose: To investigate subfoveal and perifoveal choroidal thickness (CT) in patients with rheumatoid arthritis (RA). Methods: A study group of 117 patients with RA and a control group of 46 age-matched healthy individuals were enrolled in the study. Subfoveal and perifoveal CTs were measured using enhanced depth imaging optical coherence tomography (EDI-OCT). Perifoveal CT was measured 1,500 µm nasally and 1,500 µm temporally apart from the foveal center. Relationship between the disease activity score 28 (DAS-28) and subfoveal CT was also evaluated. Results: The mean subfoveal CT values in the study and control groups were 226.90 ± 43.61 μm and 299.74 ± 48.06 μm, respectively, which made for a statistically significant difference (p < 0.001). Likewise, perifoveal CT values were significantly thinner in the study group when compared with control group. DAS-28 wasn’t correlated with subfoveal CT in the study group. Conclusions: CT was significantly thinner in patients with RA when compared with healthy controls.