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Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi, vol.34, no.6, pp.386-390, 2006 (Scopus)
Aim: We aimed to evaluate the analgesic effect of Lurnoxicam during and after the office hysteroscopy. Material and method: Fifty-two, ASA I-II, nulliparous women scheduled to have both diagnostic and minor operative office hystoroscopy, were randomly enrolled into cither Group L (n=26) (Lornoxicam) or Group P (n=26) (Placebo). Twenty-five minutes before the procedure either Lornoxicam 12 mg or saline with the same volume was administered to the patients intramuscularly. At each step of the hysteroscopy, the pain/discomfort was evaluated by patient with a 5 point scale. Patients with scores 4 (for more than 5 minutes) or 5 were sedated with iv Propofol as Patient Controlled Sedation. Results: There was no difference in disturbance/pain scores during each step of hystcroscopies between the groups. During passage through the internal cervical ostium % 34.6 of the patients showed barely tolerable pain, which was considered as the disturbance/pain score of 4. Fifty percent of the patients in the operative group reported barely tolerable to intolerable pain, disturbance/pain score of 4 to 5, during the operation. One patient required Patient Controlled Sedation with Propofol and 10 minutes following the procedure only minimal discomfort was detected in both groups, regardless of any operative procedure. There was no surgical complication or any vagal reaction. Conclusion: Lornoxicam 12 mg im before the procedure docs not provide effective analgesia during office hysteroscopy.