Diffusion-weighted imaging of the appendicular skeleton with a non-carr-purcell-meiboom-gill single-shot fast spin-echo sequence

Öner A. Y., Aggunlu L., Akpek S., TALI E. T., Celik A.

American Journal of Roentgenology, cilt.189, sa.6, ss.1494-1501, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 189 Sayı: 6
  • Basım Tarihi: 2007
  • Doi Numarası: 10.2214/ajr.07.2512
  • Dergi Adı: American Journal of Roentgenology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1494-1501
  • Anahtar Kelimeler: appendicular skeleton, avascular necrosis, bone lesions, diffusion-weighted imaging, echo-planar imaging, MR techniques, parallel imaging, perfusion imaging, VERTEBRAL COMPRESSION FRACTURES, BONE-MARROW, BENIGN, DIFFERENTIATION, ISCHEMIA
  • Lokman Hekim Üniversitesi Adresli: Hayır

Özet

OBJECTIVE. The objective of our study was to prospectively evaluate the signal-to-noise ratio (SNR) improvement in diffusion-weighted imaging (DWI) of the appendicular skeleton with the use of a newly developed non-Carr-Purcell- Meiboom-Gill (non-CPMG) single-shot fast spin-echo (SSFSE) sequence and to evaluate its effect on apparent diffusion coefficient (ADC) measurements. SUBJECTS AND METHODS. DWI of the bone was performed in 32 patients with an echo-planar imaging (EPI)-based sequence followed by a non-CPMG SSFSE technique. SNR and ADC values were measured over a lesion-free right femoral head. A score was assigned for each set of images to assess image quality. When a bone lesion was present, contrast-to-noise ratio (CNR) and ADC were also measured. Paired Student's t tests were used for statistical analysis. RESULTS. The mean (± SD) SNR values were 9.89 ± 2.20 and 81.68 ± 4.87 for EPI and non-CPMG SSFSE DWI, respectively. SNR values associated with the non-CPMG SSFSE technique were found to be significantly higher than those measured with the EPI-based DWI technique (p < 0.01). Mean ADCs of the bone were 0.57 ± 0.20 and 0.29 ± 0.15 × 10-3 mm2/s, respectively, for EPI and non-CPMG SSFSE DWI. Image quality scores were higher for the non-CPMG SSFSE DWI technique (p < 0.05) than for the EPI-based DWI technique. Overall lesion CNR was found to be higher in DWI performed with the non-CPMG SSFSE technique. CONCLUSION. The non-CPMG SSFSE technique provides a significant improvement over the currently used EPI-based DWI technique and has the potential to be a powerful tool in imaging the appendicular skeleton. © American Roentgen Ray Society.