Antibacterial effects of cinnamon oil against carbapenem resistant nosocomial Acinetobacter baumannii and Pseudomonas aeruginosa isolates

KAŞKATEPE B., Kiymaci M. E., Suzuk S., Erdem S. A., Cesur S., YILDIZ S.

Industrial Crops and Products, cilt.81, ss.191-194, 2016 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 81
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.indcrop.2015.11.058
  • Dergi Adı: Industrial Crops and Products
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.191-194
  • Anahtar Kelimeler: Acinetobacter baumannii, Antibacterial activity, Cinnamon oil, Pseudomonas aeruginosa, GC, GC/MS, FENNEL FOENICULUM-VULGARE, IN-VITRO, ANTIMICROBIAL ACTIVITIES, MEMBRANE TOXICITY, ANTIOXIDANT, OREGANO, CINNAMALDEHYDE, FOODS, L.
  • Lokman Hekim Üniversitesi Adresli: Hayır

Özet

© 2015 Elsevier B.V..Widespread existence of drug-resistant pathogens poses a threat to the successful treatment of bacterial diseases and increases the need for new antibacterial agents. Natural products are the basic source of antibacterial therapeutic agents for now, and will remain so in the future. Therefore, the aim of this study was to determine the antibacterial activity of cinnamon oil against carbapenem-resistant nosocomial isolates of Acinetobacter baumannii (111) and Pseudomonas aeruginosa (136). The essential oil composition of cinnamon oil was analyzed by GC, GC/MS and the antimicrobial effect of cinnamon oil was determined by disk diffusion method. The observed zone diameters were compared with carbapenem breakpoints (CLSI standard) and it was found that only one of the P. aeruginosa isolates was within resistance limits. Thus, cinnamon oil has antimicrobial activity with potential use as an antimicrobial agent in the pharmaceutical industry and an additive in the food industry.