Akademik Veri Yönetim Sistemi
cilt.4, sa.1, ss.48-56, 2024 (Hakemli Dergi)
Objectives: The present study investigates the factors effective in the continued sensitivity to penicillin of people with
penicillin allergies.
Methods: Included in the study were patients who presented with penicillin allergies and defined penicillin allergies
between July 1, 2013 and December 31, 2015. The sample was divided into two groups, being: those with continued
sensitivity, and those with a previous history of allergy to the group of drugs who can now use them without problems
after undergoing diagnostic tests performed following the National Guidelines for Approach to Clinical Drug Hypersensitivity to those with suspected penicillin allergy, and these two groups of patients were compared. 14, 2 and 4.
Results: Among 70 patients with penicillin allergies, 14 were excluded due to irrelevant histories or incomplete tests.
Among those with complete test results (n=36), 17 (47%) showed no persistent allergy, while 13 (36%) had persistent
allergies via skin tests, and 6 (17%) via oral provocation tests after negative skin results. Persistent allergies typically
developed within 5 years of initial reaction, ceasing after 7 years.
Conclusion: Allergic evaluations should be made based on detailed patient histories, skin tests and oral provocation tests
so as not to limit the use of penicillin unnecessarily in those with a history o