Akademik Veri Yönetim Sistemi
Akademik Gastroenteroloji Dergisi, cilt.21, sa.2, ss.53-58, 2022 (Hakemli Dergi)
Background and Aims: Previously, Helicobacter pylori infection was held responsible for changes in complete blood count and inflammatory
parameters. But changes in these parameters after eradication treatment was not entirely evaluated. This study was designed to evaluate the
effect of eradication treatment for Helicobacter pylori infection on inflammatory markers and complete blood count parameters. Materials and
Method: This single center, observational study enrolled participants who came to internal medicine outpatient clinics because of dyspeptic
complaints and who were diagnosed to have Helicobacter pylori infection after endoscopic evaluation, between July 2021 and January 2022.
Participants who were tested negative for Helicobacter pylori stool antigen test eight weeks after eradication treatment were included. Complete
blood count and infammatory parameters before and after eradication treatment were compared. Results: Mean participant age was 43.84 ±
12.59 years. There were significant decreases in erythrocyte sedimentation rate, C-reactive protein, platelet to lymphocyte ratio and neutrophile
to lymphocyte ratio after eradication. Changes in platelet counts and mean platelet volumes were insignificant. Conclusion: Erythrocyte sedimentation rate, C-reactive protein, platelet to lymphocyte ratio and neutrophile to lymphocyte ratio were significantly lower after eradication for
Helicobacter pylori. These parameters may be useful, simple, available and non-invasive tests that may be used in evaluation of eradication
treatment for Helicobacter pylori.