Molecular modeling and in vitro approaches towards cholinesterase inhibitory effect of some natural xanthohumol, naringenin, and acyl phloroglucinol derivatives

ERDOĞAN ORHAN, İLKAY; Jedrejek, Dariusz; ŞENOL DENİZ, FATMA; Salmas, Ramin; DURDAĞI, SERDAR; Kowalska, Iwona; Pecio, Lukasz; Oleszek, Wieslaw

doi:10.1016/j.phymed.2018.03.009

Molecular modeling and in vitro approaches towards cholinesterase inhibitory effect of some natural xanthohumol, naringenin, and acyl phloroglucinol derivatives

Atıf İçin Kopyala

ERDOĞAN ORHAN İ., Jedrejek D., ŞENOL DENİZ F. S., Salmas R. E., DURDAĞI S., Kowalska I., ...Daha Fazla

PHYTOMEDICINE, cilt.42, ss.25-33, 2018 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 42
Basım Tarihi: 2018
Doi Numarası: 10.1016/j.phymed.2018.03.009
Dergi Adı: PHYTOMEDICINE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.25-33
Anahtar Kelimeler: Xanthahumol, Naringenin, Acyl phloroglucinol, Cholinesterase, Molecular docking, HUMULUS-LUPULUS L., ALZHEIMERS-DISEASE, ACETYLCHOLINESTERASE INHIBITORS, PRENYLATED FLAVONOIDS, PROTEIN, ANTIOXIDANT, METABOLITES, EXTRACTS, DOCKING, SITE
Lokman Hekim Üniversitesi Adresli: Hayır

Özet

Background: Many natural products, particularly phenolic compounds, have been reported to have a strong inhibition against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), the key enzymes in the pathology of Alzheimer's disease (AD).