Akademik Veri Yönetim Sistemi
Turkiye Klinikleri Dermatoloji, cilt.34, sa.2, ss.82-88, 2024 (Scopus)
Hair loss is a common cause of presentation to dermatology outpatient clinics and an important disorder affecting the quality of life of patients. Alopecia with cicatricial and non-cicatricial subtypes is a common cause of cosmetic problems. Interest in the use of microneedling as an independent and adjunctive treatment for hair loss disorders has been increasing recently. Microneedling is a minimally invasive procedure that uses multiple needles to create micro punctures in the skin. The penetration of the microneedles produces a controlled skin injury with minimal epidermal damage and stimulates dermal wound healing, hence neovascularisation and the release of growth factors. In hair loss, the stimulation of hair growth by microneedling is related to the wound healing process that occurs in response to the trauma it creates. Microneedling therapy has been shown to stimulate hair growth through the release of various growth factors, stimulation of dermal papilla stem cells and various mechanisms. Although evidence suggests that microneedling may improve hair loss, clinical data are relatively limited. There is not yet a standardised needle length and procedure consensus for treatment and clinical data are relatively limited. With more participants and multi-centre experimental studies, microneedling may become a basic or adjunctive procedure in US Food and Drug Administration (FDA)-approved hair loss treatments. In this review, the mechanism of action of microneedling, the procedure of use with the data in the literature, and its effectiveness in androgenetic alopecia, alopecia areata, telogen effluvium and other hair loss types will be discussed in detail.