Akademik Veri Yönetim Sistemi
Handbook of the Biology and Pathology of Mental Disorders, Colin R. Martin,Victor R. Preedy,Vinood B. Patel,Rajkumar Rajendram, Editör, Springer Nature Switzerland Ag, Zug, ss.1-23, 2025
Bipolar disorder, known
as manic depressive disorder, is defined as a mood disorder with a chronic
course characterized by mania, hypomania, and successive or intertwined periods
of depression with periods of well-being between them. People with mood
disorders show higher rates of unhealthy lifestyle preferences, including poor
diet quality and malnutrition. Diet and nutrition have an impact on the brain
and mental health, but their impact on cognitive outcomes in psychiatric
disorders has been less investigated. Cases of bipolar disorder are difficult
to manage because the standard treatment approaches have limited efficacy,
resulting in a failure to recover for many patients and reduced quality of life
for bipolar individuals. However, N-acetylcysteine, vitamin D, omega-3 fatty
acids, and probiotics or the prevention of gut microbiota dysbiosis seem
promising for the treatment of bipolar disorder. The role of diet in bipolar disorder
needs to be further examined in research as it has emerged as a factor that may
change the progression of the disorder and potentially improve current treatment
outcomes. This chapter reviews studies examining the causal relationships between
diet, nutrition, and bipolar disorder and then discusses the mechanisms that
may underlie those relationships.