Hepatocellular carcinoma missed on gadolinium enhanced mr imaging, discovered in liver explants: Retrospective evaluation

KARADENİZ BİLGİLİ M. Y., Braga L., Birchard K. R., Gerber D., Firat Z., Woosley J. T., ...More

Journal of Magnetic Resonance Imaging, vol.23, no.2, pp.210-215, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 2
  • Publication Date: 2006
  • Doi Number: 10.1002/jmri.20491
  • Journal Name: Journal of Magnetic Resonance Imaging
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.210-215
  • Keywords: liver, MR, liver, HCC, HCC, contrast agents, INTRAARTERIAL INJECTION, ARTERIAL PORTOGRAPHY, CIRRHOTIC LIVER, CT, ARTERIOGRAPHY, ACQUISITION, APPEARANCE, NODULES, LESIONS
  • Lokman Hekim University Affiliated: Yes

Abstract

The main purpose of this study was to determine if hepatocellular carcinomas (HCCs) missed on prospective magnetic resonance (MR) study could be identified on retrospective MR analysis, and to determine the cause for misdiagnosis. Among 555 patients who underwent liver transplantation between 1993 and 2004, 279 were imaged with MR imaging and four of these revealed HCCs in explanted livers that were not reported on prospective MR reading. The main cause of missed lesions were suboptimal image quality due to inability of patients to suspend respiration; other causes were HCC misinterpreted as high-grade dysplastic nodule and isoenhancement of HCC on early phase images. © 2008 Wiley-Liss, Inc.