Administration of mine protocol in intermediate and high grade non- Hodkin's lymphomas Primejena Protokola mine u lijecenju nehodgikinovih limfona srednjeg i visokog stupnja

Aydogdu I., Koc H., İLHAN ., Gurman G., Akan H., Beksac M., ...Daha Fazla

Libri Oncologici, cilt.25, sa.2-3, ss.103-106, 1996 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 2-3
  • Basım Tarihi: 1996
  • Dergi Adı: Libri Oncologici
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.103-106
  • Anahtar Kelimeler: Combination chemotheraphy, Ifosfamide, Mitoxantrone, Non-Hodgkin's lymphoma
  • Lokman Hekim Üniversitesi Adresli: Evet

Özet

In recent years, more effective and less toxic treatment protocols have been developed to rise the cure rates in intermediate and high grade non- Hodgkin's lymphoma. The present study was undertaken to investigate the activity and toxicity of MINE combination chemotherapy in intermediate and high grade non-Hodgkin's lymphoma. Twenty-one patient (16 male, 5 female, age range 26 to 70 years) with non-Hodgkin's lymphoma were included in the study. An overall response rate of 73% and complete response rate of 56% were achieved. An overall survival rate for responded patients accounted for 44% at 48 months. There were not any serious side effects except mild myelosuppression, nausea-vomiting and alopecia. This study showed that MINE protocol might be an effective first-line treatment alernative for intermediate high grade patients with NHL.