Synthesis and antimicrobial activity of some novel furyl and benzimidazole substituted benzyl ethers

Güven Ö. Ö., Erdoǧan T., GÖKER A. H., YILDIZ S.

Journal of Heterocyclic Chemistry, vol.44, no.3, pp.731-734, 2007 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 3
  • Publication Date: 2007
  • Doi Number: 10.1002/jhet.5570440336
  • Journal Name: Journal of Heterocyclic Chemistry
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.731-734
  • Lokman Hekim University Affiliated: No

Abstract

(Chemical Equation Presented) In this study, a series of novel furyl and benzimidazole substituted benzyl ethers were synthesized and evaluated for antibacterial and antifungal activities against S. aureus, Methicillin resistant S. aureus (MRSA), E. coli, C. albicans and C. krusei. Compound 6f and 6h exhibited the most potent anti-bacterial activity with lowest MIC values of 3.12 μg/mL against S aureus and MRSA, respectively.